TraderVic wrote: ↑Fri Aug 29, 2025 7:33 pm
I get severe leg cramps as well. Another guy at deer camp said he keeps packets of mustard on hand and swallows the mustard when his cramps occur. He says the cramp subsides immediately. I have not confirmed this.
I have a patient who kept restaurant mustard-packets at her bedside and swears that eating a couple almost immediately eased her leg cramps enough that she could at least get up and 'walk them off'.
I measured her serum magnesium and it was normal, and her RBC magnesium was also 'normal', but since she also had constipation and trouble sleeping, we decided to try magnesium anyway; taking 3 of the 400 mg liguid-gel Magnesium Oxides (Nature's Bounty) - considered a 'basic' versus the glycinate or other forms - stopped the leg cramps from happening. She cut to two capsules and no cramps, but at one capsule the cramps resumed. So much for precision lab studies. (Rhonda Patrick has a YouTube video explaining to doctors why relying on mineral or hormone measurements is not always a good idea.)
I thought about having her try a cinnamon disk or hot ginger tea due to the proposed mechanism of mustard, but the mustard seemed to work ok, and she didn't mind the taste - once she gimped and limped to the bathroom she washed it down with water.
The mechanism of 'pickle juice' or mustard likely involves the vinegar or other acidic/irritating content - (see this article -
https://pubmed.ncbi.nlm.nih.gov/24955622/) - rather than electrolyte fixes (which would take much longer and much more volume than a mustard packet or two). The thinking is that it may be an autonomic nerve response initiated by the acidic or irritating content, which may somehow cause some sort of rapid neurologic response reflexing out of the autonomic system into the skeletal muscles, although this hasn't been proven. So the fact that the more traditional magnesium treatment helped her kind of surprised me, as it is a preventative, not a rapid-response treatment.
My thinking is that she was clinically low in magnesium (leg cramps at night, trend towards constipation, sleep difficulty only partly resolved with progesterone replacement) despite the 'normal' levels - the response to it (leg cramps prevented, bowels normalized, sleep better) more or less verified that suspicion. Perhaps before the magnesium, the cramps were stopped after-the-fact by a different mechanism caused by the mustard. It has little magnesium, and mostly is a slightly acidic thing (but not enough in the packet to change the blood pH meaningfully, even after the 15-20 minutes or more it might take to even get absorbed), that may trigger some vagal-nerve response that vasodilates blood vessles or triggers some direct muscle reaction.
The mustard thing seems to work for many people though, even if science has yet to figure out why.
I can't see much harm in it, unless someone has a really sensitive stomach, but if so, they probably won't even go near mustard...!
I enjoy oddball 'home remedy' stuff though - 80% of it is bogus (although so is 80% of 'traditional medicine'), but some of it REALLY works, and often works very well.
There is a whole group of mostly women, who are into 'essential oils' (they will tell you they can cure ANYTHING with them) - again, probably 80% bogus or placebo (but they DO smell good), but one theory on why SOAP (a bar in between the sheets near the legs) may help reduce leg cramps is that many soaps do contain 'fragrance' (i.e. 'essential oils'), and that many of those oils cause vasodilation (true), and that enough may evaporate out of the soap to cause some vascular effect in the nearby legs, easing the leg cramps -
https://www.peoplespharmacy.com/articles/why-does-soap-soothe-nighttime-leg-cramps. If so, that would be an amazingly low dose of essential oils to have that effect; I'd love to see some 'controlled experiments' to see just what the deal is. I don't think it is all 'placebo', but it would be easy enough to slip something in between the sheets that is encased in a stocking so not visible, and have half the patients get a bar of wood or something instead. Or tell them they were in a 'control' group and weren't going to get a bar of soap at all, but secretly put one there, or a bunch of shavings. Perhaps a vaporizere with vapo-rub nearby to disguise any revealing soap-smell.